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The authors conclude that the updated misoprostol regimen is highly effective and a potential strategy for expanding access to abortion. Misoprostol only is recommended by the world health organization as a safe and effective alternative to end a pregnancy with a success rate averaging 95% or better. We performed this systematic review to summarize available data on the effectiveness and safety of medical abortion with misoprostol alone in the first trimester of pregnancy.

Mifepristone and Misoprostol for Early Pregnancy Loss and Medication

You would do this three times. The evidence establishing the high effectiveness and safety of combined regimens is extensive and robust.